Drew Koch
Assistant Professor, PSRL Basic Sciences (Musculos Clinical Sciences232 Translational Medicine Institute (Tmi)
[email protected]About Drew
Drew is a veterinary surgeon, principal investigator, and assistant professor within the Preclinical Surgical Research Laboratory at Colorado State University’s Translational Medicine Institute. He completed his D.V.M. and large animal surgery residency (ACVS) at Colorado State University and his Ph.D. in comparative biomedical sciences at North Carolina State University. His research focuses on elucidating the role of stromal cell senescence in the progression and treatment of musculoskeletal and orthopedic injuries, as well as advancing and refining large animal models to study these conditions.
Education
Ph.D., North Carolina State University, 2023 Master of Science, Colorado State University, 2020 Doctor of Veterinary Medicine, Colorado State University, 2016 Bachelor of Science, Colorado State University-Pueblo, 2012Certifications
Diplomate, American College of Veterinary Surgeons (Large Animal)Publications
Nellenbach, K., Mihalko, E., Nandi, S., Koch, D. W., Shetty, J., Moretti, L., Sollinger, J., Moiseiwitsch, N., Sheridan, A., Pandit, S., Hoffman, M., Schnabel, L. V., Lyon, L. A., Barker, T. H., & Brown, A. C. (2024). Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma. Science Translational Medicine, 16(742), eadi4490. https://doi.org/10.1126/scitranslmed.adi4490 Koch, D. W., Froneberger, A., Berglund, A., Connard, S., Souther, A., & Schnabel, L. V. (2024). IL-1ß + TGF-ß2 dual-licensed mesenchymal stem cells have reduced major histocompatibility class I expression and positively modulate tenocyte migration, metabolism, and gene expression. Journal of the American Veterinary Medical Association, 262(S1), S61–S72. https://doi.org/10.2460/javma.23.12.0708 Koch, D. W., & Schnabel, L. V. (2023). Mesenchymal stem cell licensing: Enhancing MSC function as a translational approach for the treatment of tendon injury. American Journal of Veterinary Research. https://doi.org/10.2460/ajvr.23.07.0154 Little, D., Amadio, P. C., Awad, H., Cone, S., Dyment, N. A., Fisher, M. B., Huang, A. H., Koch, D. W., Kuntz, A. F., Madi, R., McGilvrey, K., Schnabel, L. V., Shetye, S. S., Thomopoulos, S., Zhao, C., & Soslowsky, L. J. (2023). Preclinical tendon and ligament models: Beyond the 3Rs (Replacement, Reduction, Refinement) to 5W1H (Why, Who, What, Where, When, How). Journal of Orthopaedic Research. https://doi.org/10.1002/jor.25678 Koch, D. W., Schnabel, L. V., Ellis, I. M., Bates, R. E., & Berglund, A. K. (2022). TGF-ß2 enhances tendon healing-associated paracrine factor expression in equine bone marrow-derived mesenchymal stem cells. Stem Cell Research & Therapy. https://doi.org/10.1186/s13287-022-03172-9Research Specialty
Preclinical animal disease models
Musculoskeletal biology
Tendinopathy